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Weighing Flavors Companies also argued that while the guidance seeks to deter youth use of e-cigarettes, it sets a high burden for authorization of fruit and candy-flavored products that the agency deems to have the potential to appeal to younger people

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The harmful chemicals present in cigarettes, such as nicotine and carbon monoxide, can interfere with the normal functioning of Leydig cells in the testes, which are responsible for testosterone production

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