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Abbreviations BALF: Bronchoalveolar lavage fluid COPD: Chronic obstructive pulmonary disease CSE: Cigarette smoke extract DMSO: Dimethyl sulfoxide ELISA: Enzyme-linked immunosorbent assay GADPH: Glyceraldehyde 3-phosphate dehydrogenase H&E: Hematoxylin and eosin IFN: Interferon, IL: Interleukin LDH: Lactate dehydrogenase MLI: Mean linear intercept MTT: 3-[4,5-imethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide NLR: Nucleotide-binding oligomerization domain-like receptor NLRP3: NLR protein-3 PBS: Phosphate-buffered saline PM 2.5 : Particulate matter of diameter 2.5 m PMSF: Phenylmethylsulfonyl fluoride QOL: Quality of life qRT-PCR: Quantitative real-time polymerase chain reaction SGRQ-C: Saint Georges respiratory questionnaire specific for COPD TUNEL: Terminal deoxynucleotidyl transferase dUTP nick end labeling References Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, et al
