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CRD42023385632) ( We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, adhering to the 4-phase flow diagram and the 27-item checklist for this study (see PRISMA reporting checklist) 6

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Kalluri R, LeBleu VS

Descriptive statistics were presented as means and standard deviations or medians and interquartile ranges for continuous variables, and as frequencies and percentages for categorical variables