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Importantly, cigarette smoke exposure has been recently associated with blunted nasal host defense against Streptococcus pneumonia , which facilitated invasive pneumococcal disease [57]

Then, AMcN, SCH and CNET jointly reviewed the coded data relating to why participants initiated, continued, and discontinued IQOS more inductively

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The other model instead added a continuous covariate for time, as measured by the number of years between period midpoints relative to the first period, and produced a p-value from a t-test to assess a linear ANA time trend