Osteoporosis Smoking can cause a drop in bone density
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For the FeNO recording, the subjects were studied in the sitting position wearing a nose-clip and were asked to inhale as deeply as they could, to total lung capacity, while breathing through a mouthpiece and then to ex- hale at a flow rate of about 50 mL/s, maintaining a con- stant mouth pressure of 4 to 5 cm H 2 O for 10 s, aided by visual feedback on the screen of the instrument
