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Traditional cigarettes, which burn tobacco to deliver nicotine, are widely recognised as harmful due to the release of thousands of toxic chemicals, tar, and carcinogens when the tobacco is burned

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[11] In 2022, JTI and Altria announced a strategic partnership to sell JTI's successful Ploom product in the U.S

During the WrC20 period, the energy metabolism and amino acid metabolism of the bacterial community were active, indicating that the dominant bacterial community started a massive growth and reproduction process at this time