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Considered a sacred plant by almost all Native American tribes, it has been used medicinally to treat sprains, bruises, and infected wounds, as well as ceremonially as a conduit for communing with local deities or as an offering to animist spirits
The British Broadcasting Corporation
With respect to safety, NPs were generally very well tolerated with no serious AEs noted after administration, while six participants reported minor AEs (dizziness, headache, hot flush, hyperhidrosis and back pain) that resolved quickly