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Studies in various countries have found that middle-aged smokers have two to three times the mortality rate of non-smokers of similar age, reducing lifespan by an average of 10 years

This is why rescheduling can take months or years and may include public hearings

At the end of the four-month trial, significantly greater numbers of participants assigned to the active group (26%) were able to sustain reduction (reduced smoking by at least 50% from week six) compared to the placebo condition (9%)

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This, in turn, could provide new insights that may help to refine existing treatment approaches for nicotine dependence