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Additionally, smoking can negatively influence the phagocytic activity of immune cells [13]

The majority of PVL cases are not associated with tobacco smoking or other suspected risk factors for traditional leukoplakia and squamous cell carcinoma

Thirdhand smoke Thirdhand smoke (THS) refers to the persisting particulate matter that becomes embedded in environments exposed to cigarette smoke, even after the smoke has cleared from the air

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In other countries (Sweden, Norway, Iceland), this is mainly due to increasing smoking-attributable mortality in females