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But, that doesnt take away from the fact that they can be classed as gateway drugs, especially for those who may be more at risk of developing addiction due to genetics, environment, or just personal circumstances

In addition, a biopsychosocial approach is recommended rather than medication alone ( 102 )

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Nicotine has a negative impact on the synapses that connect brain cells

For the replacement method to work, you have to figure out how to maintain a normal (for you) level of caffeine in your blood while you gradually reduce that level over a two-week period