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Acetaldehyde inhibits neutrophil apoptosis, prevents neutrophil-mediated killing of pathogens, and contributes to neutrophil accumulation, resulting in a delay in resolution of inflammation ( High levels of these reactive aldehydes form adducts on macromolecules present in the lungs, leading to an inflammatory response

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a smokers lung X-ray reveals the stark contrast in lung clarity and condition, highlighting the severe impact of smoking on respiratory health