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To be clear, this is not about comparing nicotine to caffeine. Come on. But vaping heavy-hitters have made the caffeine-nicotine link explicitly, too like when Juuls co-founder bemoaned the stigmatization of nicotine compared to caffeine in his conversation with The Mercury News

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Mitochondrial reactive oxygen species cause major oxidative mitochondrial DNA damages and repair pathways

"The effect sizes were actually quite large and meaningful, given the number of people who might be exposed to this marketing strategy," Duan said in a university news release

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