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If after 6 weeks the antihistamines are not working, other treatments may be recommended: Your doctor may recommend a biologic treatment to treat your chronic hives: Omalizumab (XOLAIR), a medicine approved by the Food and Drug Administration (FDA) for the treatment of CSU in people aged 12 years and older

Friedman, 2015

Although the site has been investigated, little reconstruction work has taken place

I'm sure at some point or another we have all, or someday will, experience a feeling similar to that: the feeling that you have lost who you used to be