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Centers for Disease Control analyzed 2000-2009 data from the National Youth Tobacco Survey on tobacco use and found a significant decline over the decade

A systematic review found that e-cigarettes were associated with myriad respiratory health effects such as exacerbations of asthma, eosinophilic pneumonia, epiglottitis, bronchitis, and acute respiratory distress 35

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These effects include increasing your heart rate and the blood flow to your heart, and the hardening and narrowing of your arteries, so more blood has to flow through a tighter area, increasing your blood pressure