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You've got me, but this snappy tune had Fifties' audiences (and transformers) humming

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Impairments of the OFC may result in enhanced stress reactivity and inability to contain emotional moods (Bechara et al., We also revealed that better smoking cessation outcomes were related to greater right putamen and caudate nucleus (dorsal striatum) GM volume at baseline

With repeated exposure, the brain upregulates (increases) the number of these receptors and becomes dependent on nicotine to maintain normal dopamine signaling

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