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Front Immunol 13:826889 Acknowledgements We would like to express our heartfelt thanks to all the participants in this study

Authors' contributions The DCOT investigators designed the study

The defense hung tough for the first 20 or so of 48 snaps, but the two big-play touchdowns on either side of halftime were a result of getting outschemed and outplayed

There is no definitive answer to what the best policy solutions are to control the use of e-cigarettes around the world, as different countries have different legal, cultural and social contexts that influence health policy to affect the regulation and use of e-cigarettes

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