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Results Among the 12,144,972 women included, 9.3% smoked before pregnancy and 7.0%, 6.0%, and 5.7% in the first, second, and third trimester, respectively
Further research, including pharmacokinetic studies in smokers versus nonsmokers, is warranted to clarify the impact of smoking on ifosfamide and cyclophosphamide levels, and nicotines impact on cancer cell biology and chemosensitivity
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