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A few studies of persons with traumatic brain injury have found that alcohol use gets worse in the period 2 to 5 years after the injury and that unless something is preventing them, many resume their prior levels of alcohol and other drug use (Corrigan, Rust et al., 1995

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Randomized control trials are needed to more firmly assess the potential of heated tobacco as a means of quitting cigarettes, but it would not be surprising to see a similar dynamic at play