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A significant limitation of the study was the relatively small number of people who were using e-cigarettes at the beginning of the trial, making it difficult to be confident that the results would be replicated in a larger e-cigarette user sample

Our definition of spliffs did not include blunts, which can be detailed in future research

The rise in blood pressure is due both to an increase in cardiac output and in total peripheral vascular resistance. Interestingly, the study also noted that while the act of smoking causes spikes in blood pressure, stopping smoking can also have the same effect as a part of withdrawal, describing the effect as a paradox

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