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Interestingly, although Sam depletion leads to a decrease in mitochondrial mass and subsequent aggregation of PINK1, this mechanism does not affect mitochondria to the extent of mtDNA

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This notionthat an enlightened person can be an addicted personmight shatter our preconceptions about realization, but to practice Buddhism and believe ones preconceptions will remain neatly intact seems about as nave as believing a teacher is a divine being