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While some studies suggest potential harm from heavy, long-term use, others hint at potential benefits, particularly regarding THC and Alzheimer's disease

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A possible mechanism would be that inhibition of hepatic cholesterol synthesis impairs bile acid production in a manner similar to the coordinated inhibition of both cholesterol and bile acid synthesis by lovastatin in humans, while apoE-rich lipoproteins distribute excess absorbed cholesterol directly into the bile [66]

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