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Pro Tip: If you've tried a pouch at a given mg and found it underwhelming, try the same brand in a moist slim format before jumping to a higher strength

The leaves are partially dried to ensure that they are still supple so the stems on the leaves and any remaining dirt can be easily removed

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Titration phase (weeks 37) Participants in groups A and B will receive an active nicotine patch (21 mg/day) for the entire titration phase in addition to escalating doses of either active patches (group A) or placebo patches (group B) per the following dose titration protocol

Oral nicotine products, including nicotine pouches, lozenges, and gums, have surged in popularity in recent years