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Neuropharmacology 44:642652 Crowley-Weber CL, Dvorakova K, Crowley C, Bernstein H, Bernstein C, Garewal H, Payne CM (2003) Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis

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Vaping may help re-normalize tobacco use and get kids started, even leading them to regular cigarettes over time

For reasons that are not fully understood, the risk for women was somewhat smaller - 31 and 34 per cent, respectively